DASHA - Revision history

Bugman: removed Category:Software; added Category:Model-free software using HotCat

2020-10-21T15:49:52Z

removed Category:Software; added Category:Model-free software using HotCat

Bugman: /* Version */ Use of the {{current version DASHA}} template.

2015-12-16T12:57:47Z

Version: Use of the {{current version DASHA}} template.

Bugman: Added the Category:Software category.

2015-12-15T15:55:14Z

Added the Category:Software category.

Bugman: Changed the sectioning and listed the relax user functions for DASHA.

2015-12-15T15:16:54Z

Changed the sectioning and listed the relax user functions for DASHA.

Bugman: Bugman moved page Dasha to DASHA: Match the capitalisation used by the original authors.

2015-12-15T15:08:56Z

Bugman moved page Dasha to DASHA: Match the capitalisation used by the original authors.

Bugman: Capitalised all of DASHA.

2015-12-15T15:06:24Z

Capitalised all of DASHA.

Bugman: Added the Orekhov95 reference.

2015-12-15T15:04:47Z

Added the Orekhov95 reference.

Bugman: Created a page for the Dasha model-free software.

2015-12-15T14:59:54Z

Created a page for the Dasha model-free software.

New page

The software Dasha is designed for the model-free analysis for NMR relaxation data. Dasha can be used as an optimisation engine to replace the minimisation algorithms implemented within relax.

== Website ==

The original Dasha website is http://www.nmr.ru/dasha.html (and [https://web.archive.org/web/20150223190004/http://www.nmr.ru/dasha.html archived on the Internet Archive]).

== Overview ==

From the Dasha homepage:

{{quote|text=DASHA is an interactive program designed to investigate dynamics of biomolecules, for which data of 15N or 13C heteronuclear relaxation are available from NMR measurements. A number of sets of longitudinal and transverse relaxation rates of 15N or 13C nuclei and 1H-15N, 13C NOE's obtained at various NMR spectrometer frequencies might be used as the input. The measured longitudinal, transverse relaxation rates and NOE values are interpreted using the model-free approach of Lipari and Szabo (1982, J. Am. Chem. Soc., 104, 4546-4559). In addition to the overall rotational correlation time of the molecule, the internal dynamics of backbone N-H or C-H vectors of two types of internal motions - fast, on a time scale of <20 ps, and intermediate, close to 1 ns could be evaluated by constructing correspondent spectral density functions. Contribution of the conformational exchange to transverse relaxation rates of individual nitrogens or carbons could be elucidated using a set of different rates of the CPMG spin-lock pulse train in measuring {{:T2}} relaxation times (Orekhov et al., 1994, Eur. J. Biochem., 219, 887-896). Separate module DIFFC, included into the DASHA software, performs hydrodynamic calculations for proteins with known spatial structure. All input and output data could be easily presented in PostScript format.}}

== Authors ==

* Vladislav Yu. Orekhov
* Dmitry M. Korzhnev
* Dmitry E. Nolde
* Alexander P. Golovanov
* Alexander S. Arseniev.

== Version ==

The last release was 3.48c in May 2000.

== See also ==

[[Category:Model-free analysis]]

← Older revision		Revision as of 15:49, 21 October 2020
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	[[Category:Model-free analysis]]		[[Category:Model-free analysis]]
−	[[Category:~~Software~~]]	+	[[Category:Model-free software]]

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 === Version ===
-The last release was 3.48c in May 2000.
+The last release was {{current version DASHA}} in May 2000.
 === Reference ===

← Older revision		Revision as of 15:55, 15 December 2015
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	[[Category:Model-free analysis]]		[[Category:Model-free analysis]]
		+	[[Category:Software]]

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 The software DASHA is designed for the model-free analysis for NMR relaxation data.  DASHA can be used as an optimisation engine to replace the minimisation algorithms implemented within relax.
-== Website ==
+== Details ==
 The original DASHA website is http://www.nmr.ru/dasha.html (and [https://web.archive.org/web/20150223190004/http://www.nmr.ru/dasha.html archived on the Internet Archive]).
-== Overview ==
+=== Overview ===
 From the DASHA homepage:
@@ Line 11: / Line 13: @@
 {{quote|text=DASHA is an interactive program designed to investigate dynamics of biomolecules, for which data of <sup>15</sup>N or <sup>13</sup>C heteronuclear relaxation are available from NMR measurements. A number of sets of longitudinal and transverse relaxation rates of <sup>15</sup>N or <sup>13</sup>C nuclei and <sup>1</sup>H-<sup>15</sup>N, <sup>13</sup>C NOE's obtained at various NMR spectrometer frequencies might be used as the input. The measured longitudinal, transverse relaxation rates and NOE values are interpreted using the model-free approach of Lipari and Szabo (1982, J. Am. Chem. Soc., 104, 4546-4559). In addition to the overall rotational correlation time of the molecule, the internal dynamics of backbone N-H or C-H vectors of two types of internal motions - fast, on a time scale of &lt;20 ps, and intermediate, close to 1 ns could be evaluated by constructing correspondent spectral density functions. Contribution of the conformational exchange to transverse relaxation rates of individual nitrogens or carbons could be elucidated using a set of different rates of the CPMG spin-lock pulse train in measuring {{:T2}} relaxation times (Orekhov et al., 1994, Eur. J. Biochem., 219, 887-896). Separate module DIFFC, included into the DASHA software, performs hydrodynamic calculations for proteins with known spatial structure. All input and output data could be easily presented in PostScript format.}}
-== Authors ==
+=== Authors ===
 * Vladislav Yu. Orekhov
@@ Line 19: / Line 21: @@
 * Alexander S. Arseniev.
-== Version ==
+=== Version ===
 The last release was 3.48c in May 2000.
-== Reference ==
+=== Reference ===
 * {{#lst:Citations|Orekhov95}}
 == See also ==
 [[Category:Model-free analysis]]

← Older revision	Revision as of 15:08, 15 December 2015
(No difference)