View source for NS MMQ 3-site

The 3-site relaxation dispersion model for the numeric solution (NS) to the Bloch-McConnell equations for [[:Category:MMQ CPMG data|MMQ CPMG-type data]] whereby the simplification {{:R2Azero}} = {{:R2Bzero}} = {{:R2Czero}} is assumed.

== Parameters ==

The NS MMQ 3-site model has the parameters {{{:R2zero}}, ..., {{:pA}}, {{:pB}}, {{:DeltaomegaAB}}, {{:DeltaomegaBC}}, {{:DeltaomegaHAB}}, {{:DeltaomegaHBC}}, {{:kexAB}}, {{:kexBC}}, {{:kexAC}}}.

== Reference ==

The references for the NS MMQ 3-site model are:

* Korzhnev, D. M., Kloiber, K., Kanelis, V., Tugarinov, V., and Kay, L. E. (2004).  Probing slow dynamics in high molecular weight proteins by methyl-TROSY NMR spectroscopy: application to a 723-residue enzyme. ''J. Am. Chem. Soc.'', '''126'''(12), 3964-3973. ([http://dx.doi.org/10.1021/ja039587i 10.1021/ja039587i]).
* Korzhnev, D. M., Kloiber, K., and Kay, L. E. (2004).  Multiple-quantum relaxation dispersion NMR spectroscopy probing millisecond time-scale dynamics in proteins: theory and application. ''J. Am. Chem. Soc.'', '''126'''(23), 7320-7329. ([http://dx.doi.org/10.1021/ja049968b 10.1021/ja049968b]).
* Korzhnev, D. M., Neudecker, P., Mittermaier, A., Orekhov, V. Y., and Kay, L. E. (2005).  Multiple-site exchange in proteins studied with a suite of six NMR relaxation dispersion experiments: an application to the folding of a Fyn SH3 domain mutant. ''J. Am. Chem. Soc.'', '''127'''(44), 15602-15611. ([http://dx.doi.org/10.1021/ja054550e 10.1021/ja054550e]).

== Links ==

The [[Relaxation dispersion citation for relax|implementation of the NS MMQ 3-site model in relax]] can be seen in the:
* [http://www.nmr-relax.com/manual/The_NS_MMQ_3_site_model.html relax manual], 
* [http://www.nmr-relax.com/api/3.1/lib.dispersion.ns_mmq_3site-module.html API documentation],
* [http://www.nmr-relax.com/analyses/relaxation_dispersion.html#NS_MMQ_3-site relaxation dispersion page of the relax website].

== See also ==
[[Category:MMQ CPMG data]]
[[Category:Relaxation dispersion analysis]]