Difference between revisions of "TSMFK01"

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= Intro =
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This is the model for 2-site very-slow exchange model for time scales within range of microsecond to second time scale, where {{:pA}} ≫ {{:pB}}, and named after Tollinger et al. (2001).  This model is labelled as '''TSMFK01''' in [[Relaxation dispersion citation for relax|relax]].  A particularly interesting feature of the dispersion curves is the damped oscillations, which occur at low CPMG field strengths, and is solely a function of the chemical shift difference between the two sites (i.e., independent of the rate of exchange).
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This is the model for 2-site very-slow exchange model for time scales within range of microsecond to second time scale, where $p_A \gg p_B$, and named after Tollinger et al. (2001).  This model is labelled as '''TSMFK01''' in [[Relaxation dispersion citation for relax|relax]].  A particularly interesting feature of the dispersion curves is the damped oscillations, which occur at low CPMG field strengths, and is solely a function of the chemical shift difference between the two sites (i.e., independent of the rate of exchange).
 
  
 
== Parameters ==
 
== Parameters ==
  
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The TSMFK01 model has the parameters {$R_{2A}^0$, $...$, $\Delta\omega$, $k_{AB}$}.
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The TSMFK01 model has the parameters {{{:R2Azero}}, ..., {{:Deltaomega}}, {{:kAB}}}.
  
 
== Reference ==
 
== Reference ==
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The reference for the TSMFK01 model is:
 
The reference for the TSMFK01 model is:
  
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* Tollinger, M., Skrynnikov, N. R., Mulder, F. A. A., Forman-Kay, J. D., and Kay, L. E. (2001).  Slow dynamics in folded and unfolded states of an sh3 domain. ''J. Am. Chem. Soc.'', '''123'''(46), 11341-11352. ([http://dx.doi.org/10.1021/ja011300z 10.1021/ja011300z])
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* {{#lst:Citations|Tollinger01}}
  
 
== Links ==
 
== Links ==
  
 
The [[Relaxation dispersion citation for relax|implementation of the TSMFK01 model in relax]] can be seen in the:
 
The [[Relaxation dispersion citation for relax|implementation of the TSMFK01 model in relax]] can be seen in the:
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* [http://www.nmr-relax.com/manual/TSMFK01_2_site_CPMG_model.html relax manual],
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* [http://www.nmr-relax.com/manual/The_TSMFK01_2_site_CPMG_model.html relax manual],
 
* [http://www.nmr-relax.com/api/3.1/lib.dispersion.tsmfk01-module.html API documentation],
 
* [http://www.nmr-relax.com/api/3.1/lib.dispersion.tsmfk01-module.html API documentation],
 
* [http://www.nmr-relax.com/analyses/relaxation_dispersion.html#TSMFK01 relaxation dispersion page of the relax website].
 
* [http://www.nmr-relax.com/analyses/relaxation_dispersion.html#TSMFK01 relaxation dispersion page of the relax website].
  
 
== See also ==
 
== See also ==
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[[Category:Relaxation_dispersion]]
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[[Category:Models]]
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[[Category:Dispersion models]]
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[[Category:Relaxation dispersion analysis]]

Latest revision as of 16:47, 6 November 2015

This is the model for 2-site very-slow exchange model for time scales within range of microsecond to second time scale, where pA ≫ pB, and named after Tollinger et al. (2001). This model is labelled as TSMFK01 in relax. A particularly interesting feature of the dispersion curves is the damped oscillations, which occur at low CPMG field strengths, and is solely a function of the chemical shift difference between the two sites (i.e., independent of the rate of exchange).

Parameters

The TSMFK01 model has the parameters {R2A0, ..., Δω, kAB}.

Reference

The reference for the TSMFK01 model is:

  • Tollinger, M., Skrynnikov, N. R., Mulder, F. A. A., Forman-Kay, J. D., and Kay, L. E. (2001). Slow dynamics in folded and unfolded states of an sh3 domain. J. Am. Chem. Soc., 123(46), 11341-11352. (DOI: 10.1021/ja011300z)

Links

The implementation of the TSMFK01 model in relax can be seen in the:

See also