Difference between revisions of "TSMFK01"

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This is the model for 2-site very-slow exchange model for time scales within range of microsecond to second time scale, where $p_A \gg p_B$, and named after Tollinger et al. (2001).  This model is labelled as '''TSMFK01''' in relax.  A particularly interesting feature of the dispersion curves is the damped oscillations, which occur at low CPMG field strengths, and is solely a function of the chemical shift difference between the two sites (i.e., independent of the rate of exchange).
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This is the model for 2-site very-slow exchange model for time scales within range of microsecond to second time scale, where {{:pA}} ≫ {{:pB}}, and named after Tollinger et al. (2001).  This model is labelled as '''TSMFK01''' in [[Relaxation dispersion citation for relax|relax]].  A particularly interesting feature of the dispersion curves is the damped oscillations, which occur at low CPMG field strengths, and is solely a function of the chemical shift difference between the two sites (i.e., independent of the rate of exchange).
  
 
== Parameters ==
 
== Parameters ==
  
The TSMFK01 model has the parameters {$R_{2A}^0$, $...$, $\Delta\omega$, $k_{AB}$}.
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The TSMFK01 model has the parameters {{{:R2Azero}}, ..., {{:Deltaomega}}, {{:kAB}}}.
  
 
== Reference ==
 
== Reference ==
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The reference for the TSMFK01 model is:
 
The reference for the TSMFK01 model is:
  
* Tollinger, M., Skrynnikov, N. R., Mulder, F. A. A., Forman-Kay, J. D., and Kay, L. E. (2001).  Slow dynamics in folded and unfolded states of an sh3 domain. ''J. Am. Chem. Soc.'', '''123'''(46), 11341-11352. ([http://dx.doi.org/10.1021/ja011300z 10.1021/ja011300z])
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* {{#lst:Citations|Tollinger01}}
  
 
== Links ==
 
== Links ==
  
The implementation of the TSMFK01 model in relax can be seen in the:
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The [[Relaxation dispersion citation for relax|implementation of the TSMFK01 model in relax]] can be seen in the:
* [http://www.nmr-relax.com/manual/TSMFK01_2_site_CPMG_model.html relax manual],
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* [http://www.nmr-relax.com/manual/The_TSMFK01_2_site_CPMG_model.html relax manual],
 
* [http://www.nmr-relax.com/api/3.1/lib.dispersion.tsmfk01-module.html API documentation],
 
* [http://www.nmr-relax.com/api/3.1/lib.dispersion.tsmfk01-module.html API documentation],
 
* [http://www.nmr-relax.com/analyses/relaxation_dispersion.html#TSMFK01 relaxation dispersion page of the relax website].
 
* [http://www.nmr-relax.com/analyses/relaxation_dispersion.html#TSMFK01 relaxation dispersion page of the relax website].
  
 
== See also ==
 
== See also ==
[[Category:Relaxation_dispersion]]
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[[Category:Models]]
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[[Category:Dispersion models]]
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[[Category:Relaxation dispersion analysis]]

Latest revision as of 16:47, 6 November 2015

This is the model for 2-site very-slow exchange model for time scales within range of microsecond to second time scale, where pApB, and named after Tollinger et al. (2001). This model is labelled as TSMFK01 in relax. A particularly interesting feature of the dispersion curves is the damped oscillations, which occur at low CPMG field strengths, and is solely a function of the chemical shift difference between the two sites (i.e., independent of the rate of exchange).

Parameters

The TSMFK01 model has the parameters {R2A0, ..., Δω, kAB}.

Reference

The reference for the TSMFK01 model is:

  • Tollinger, M., Skrynnikov, N. R., Mulder, F. A. A., Forman-Kay, J. D., and Kay, L. E. (2001). Slow dynamics in folded and unfolded states of an sh3 domain. J. Am. Chem. Soc., 123(46), 11341-11352. (DOI: 10.1021/ja011300z)

Links

The implementation of the TSMFK01 model in relax can be seen in the:

See also