Difference between revisions of "NS MMQ 2-site"

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(Updated the NS MMQ 2-site page for the new dispersion model format.)
(→‎See also: Added more categories.)
 
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The relaxation dispersion model for the numeric solution (NS) to the Bloch-McConnell equations for [[MMQ CPMG-type data]].
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The relaxation dispersion model for the numeric solution (NS) to the Bloch-McConnell equations for [[:Category:MMQ CPMG data|MMQ CPMG-type data]].  This model is labelled as '''NS MMQ 2-site''' in [[Relaxation dispersion citation for relax|relax]].
  
 
== Parameters ==
 
== Parameters ==
  
The NS MMQ 2-site model has the parameters {$R_2^0$, $...$, $p_A$, $\Delta\omega$, $\Delta\omega^H$, $k_{ex}$}.
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The NS MMQ 2-site model has the parameters {{{:R2zero}}, ..., {{:pA}}, {{:Deltaomega}}, {{:DeltaomegaH}}, {{:kex}}}.
  
 
== Reference ==
 
== Reference ==
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The references for the NS MMQ 2-site model are:
 
The references for the NS MMQ 2-site model are:
  
* Korzhnev, D. M., Kloiber, K., Kanelis, V., Tugarinov, V., and Kay, L. E. (2004).  Probing slow dynamics in high molecular weight proteins by methyl-TROSY NMR spectroscopy: application to a 723-residue enzyme. ''J. Am. Chem. Soc.'', '''126'''(12), 3964-3973. ([http://dx.doi.org/10.1021/ja039587i 10.1021/ja039587i]).
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* {{#lst:Citations|Korzhnev04a}}
* Korzhnev, D. M., Kloiber, K., and Kay, L. E. (2004).  Multiple-quantum relaxation dispersion NMR spectroscopy probing millisecond time-scale dynamics in proteins: theory and application. ''J. Am. Chem. Soc.'', '''126'''(23), 7320-7329. ([http://dx.doi.org/10.1021/ja049968b 10.1021/ja049968b]).
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* Korzhnev, D. M., Neudecker, P., Mittermaier, A., Orekhov, V. Y., and Kay, L. E. (2005).  Multiple-site exchange in proteins studied with a suite of six NMR relaxation dispersion experiments: an application to the folding of a Fyn SH3 domain mutant. ''J. Am. Chem. Soc.'', '''127'''(44), 15602-15611. ([http://dx.doi.org/10.1021/ja054550e 10.1021/ja054550e]).
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* {{#lst:Citations|Korzhnev04b}}
 +
 
 +
* {{#lst:Citations|Korzhnev05a}}
  
 
== Links ==
 
== Links ==
  
The implementation of the MMQ CR72 model in relax can be seen in the:
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The [[Relaxation dispersion citation for relax|implementation of the NS MMQ 2-site model in relax]] can be seen in the:
* [http://www.nmr-relax.com/manual/NS_MMQ_2_site_model.html relax manual],  
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* [http://www.nmr-relax.com/manual/The_NS_MMQ_2_site_model.html relax manual],  
 
* [http://www.nmr-relax.com/api/3.1/lib.dispersion.ns_mmq_2site-module.html API documentation],
 
* [http://www.nmr-relax.com/api/3.1/lib.dispersion.ns_mmq_2site-module.html API documentation],
* [http://www.nmr-relax.com/analyses/relaxation_dispersion.html relaxation dispersion page of the relax website].
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* [http://www.nmr-relax.com/analyses/relaxation_dispersion.html#NS_MMQ_2-site relaxation dispersion page of the relax website].
  
 
== See also ==
 
== See also ==
[[Category:Relaxation_dispersion]]
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[[Category:Models]]
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[[Category:Dispersion models]]
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[[Category:MMQ CPMG data]]
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[[Category:Relaxation dispersion analysis]]

Latest revision as of 16:47, 6 November 2015

The relaxation dispersion model for the numeric solution (NS) to the Bloch-McConnell equations for MMQ CPMG-type data. This model is labelled as NS MMQ 2-site in relax.

Parameters

The NS MMQ 2-site model has the parameters {R20, ..., pA, Δω, ΔωH, kex}.

Reference

The references for the NS MMQ 2-site model are:

  • Korzhnev, D. M., Kloiber, K., Kanelis, V., Tugarinov, V., and Kay, L. E. (2004). Probing slow dynamics in high molecular weight proteins by methyl-TROSY NMR spectroscopy: application to a 723-residue enzyme. J. Am. Chem. Soc., 126(12), 3964-3973. (DOI: 10.1021/ja039587i)
  • Korzhnev, D. M., Kloiber, K., and Kay, L. E. (2004). Multiple-quantum relaxation dispersion NMR spectroscopy probing millisecond time-scale dynamics in proteins: theory and application. J. Am. Chem. Soc., 126(23), 7320-7329. (DOI: 10.1021/ja049968b)
  • Korzhnev, D. M., Neudecker, P., Mittermaier, A., Orekhov, V. Y., and Kay, L. E. (2005). Multiple-site exchange in proteins studied with a suite of six NMR relaxation dispersion experiments: an application to the folding of a Fyn SH3 domain mutant. J. Am. Chem. Soc., 127(44), 15602-15611. (DOI: 10.1021/ja054550e)

Links

The implementation of the NS MMQ 2-site model in relax can be seen in the:

See also