Trusted, Bureaucrats
4,228
edits
Changes
Jump to navigation
Jump to search
Created an initial NS MMQ 3-site relaxation dispersion model page.
The 3-site relaxation dispersion model for the numeric solution (NS) to the Bloch-McConnell equations for [[MMQ CPMG-type data]] whereby the simplification $R^0_{2A} = R^0_{2B} = R^0_{2C}$ is assumed.
== Parameters ==
The NS MMQ 3-site model has the parameters {$R_2^0$, $...$, $p_A$, $p_B$, $\Delta\omega_{AB}$, $\Delta\omega_{BC}$, $\Delta\omega^H_{AB}$, $\Delta\omega^H_{BC}$, $k_{ex}^{AB}$, $k_{ex}^{BC}$, $k_{ex}^{AC}$}.
== Reference ==
The references for the NS MMQ 3-site model are:
* Korzhnev, D. M., Kloiber, K., Kanelis, V., Tugarinov, V., and Kay, L. E. (2004). Probing slow dynamics in high molecular weight proteins by methyl-TROSY NMR spectroscopy: application to a 723-residue enzyme. ''J. Am. Chem. Soc.'', '''126'''(12), 3964-3973. ([http://dx.doi.org/10.1021/ja039587i 10.1021/ja039587i]).
* Korzhnev, D. M., Kloiber, K., and Kay, L. E. (2004). Multiple-quantum relaxation dispersion NMR spectroscopy probing millisecond time-scale dynamics in proteins: theory and application. ''J. Am. Chem. Soc.'', '''126'''(23), 7320-7329. ([http://dx.doi.org/10.1021/ja049968b 10.1021/ja049968b]).
* Korzhnev, D. M., Neudecker, P., Mittermaier, A., Orekhov, V. Y., and Kay, L. E. (2005). Multiple-site exchange in proteins studied with a suite of six NMR relaxation dispersion experiments: an application to the folding of a Fyn SH3 domain mutant. ''J. Am. Chem. Soc.'', '''127'''(44), 15602-15611. ([http://dx.doi.org/10.1021/ja054550e 10.1021/ja054550e]).
== Links ==
The implementation of the NS MMQ 3-site model in relax can be seen in the:
* [http://www.nmr-relax.com/manual/NS_MMQ_3_site_model.html relax manual],
* [http://www.nmr-relax.com/api/3.1/lib.dispersion.ns_mmq_3site-module.html API documentation],
* [http://www.nmr-relax.com/analyses/relaxation_dispersion.html#NS_MMQ_3-site_linear relaxation dispersion page of the relax website].
== See also ==
[[Category:Relaxation_dispersion]]
== Parameters ==
The NS MMQ 3-site model has the parameters {$R_2^0$, $...$, $p_A$, $p_B$, $\Delta\omega_{AB}$, $\Delta\omega_{BC}$, $\Delta\omega^H_{AB}$, $\Delta\omega^H_{BC}$, $k_{ex}^{AB}$, $k_{ex}^{BC}$, $k_{ex}^{AC}$}.
== Reference ==
The references for the NS MMQ 3-site model are:
* Korzhnev, D. M., Kloiber, K., Kanelis, V., Tugarinov, V., and Kay, L. E. (2004). Probing slow dynamics in high molecular weight proteins by methyl-TROSY NMR spectroscopy: application to a 723-residue enzyme. ''J. Am. Chem. Soc.'', '''126'''(12), 3964-3973. ([http://dx.doi.org/10.1021/ja039587i 10.1021/ja039587i]).
* Korzhnev, D. M., Kloiber, K., and Kay, L. E. (2004). Multiple-quantum relaxation dispersion NMR spectroscopy probing millisecond time-scale dynamics in proteins: theory and application. ''J. Am. Chem. Soc.'', '''126'''(23), 7320-7329. ([http://dx.doi.org/10.1021/ja049968b 10.1021/ja049968b]).
* Korzhnev, D. M., Neudecker, P., Mittermaier, A., Orekhov, V. Y., and Kay, L. E. (2005). Multiple-site exchange in proteins studied with a suite of six NMR relaxation dispersion experiments: an application to the folding of a Fyn SH3 domain mutant. ''J. Am. Chem. Soc.'', '''127'''(44), 15602-15611. ([http://dx.doi.org/10.1021/ja054550e 10.1021/ja054550e]).
== Links ==
The implementation of the NS MMQ 3-site model in relax can be seen in the:
* [http://www.nmr-relax.com/manual/NS_MMQ_3_site_model.html relax manual],
* [http://www.nmr-relax.com/api/3.1/lib.dispersion.ns_mmq_3site-module.html API documentation],
* [http://www.nmr-relax.com/analyses/relaxation_dispersion.html#NS_MMQ_3-site_linear relaxation dispersion page of the relax website].
== See also ==
[[Category:Relaxation_dispersion]]
