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NS MMQ 3-site

838 bytes removed, 16:47, 6 November 2015
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= Intro =The 3-site relaxation dispersion model for the numeric solution (NS) to the Bloch-McConnell equations for [[:Category:MMQ CPMG data|MMQ CPMG-type data]] whereby the simplification $R^0_{2A{:R2Azero}} = R^0_{2B{:R2Bzero}} = R^0_{2C{:R2Czero}}$ is assumed.
== Parameters ==
The NS MMQ 3-site model has the parameters {$R_2^0${{:R2zero}}, $...$, $p_A${{:pA}}, $p_B${{:pB}}, $\Delta\omega_{AB{:DeltaomegaAB}}$, $\Delta\omega_{BC{:DeltaomegaBC}}$, $\Delta\omega^H_{AB{:DeltaomegaHAB}}$, $\Delta\omega^H_{BC{:DeltaomegaHBC}}$, $k_{ex{:kexAB}^{AB}$, $k_{ex{:kexBC}^{BC}$, $k_{ex{:kexAC}^{AC}$}.
== Reference ==
The references for the NS MMQ 3-site model are:
* Korzhnev, D. M., Kloiber, K., Kanelis, V., Tugarinov, V., and Kay, L. E. (2004). Probing slow dynamics in high molecular weight proteins by methyl-TROSY NMR spectroscopy{{#lst: application to a 723-residue enzyme. ''J. Am. Chem. Soc.'', '''126'''(12), 3964-3973. ([http://dx.doi.org/10.1021/ja039587i 10.1021/ja039587i]).Citations|Korzhnev04a}} * Korzhnev, D. M., Kloiber, K., and Kay, L. E. (2004). Multiple-quantum relaxation dispersion NMR spectroscopy probing millisecond time-scale dynamics in proteins{{#lst: theory and application. ''J. Am. Chem. Soc.'', '''126'''(23), 7320-7329. ([http://dx.doi.org/10.1021/ja049968b 10.1021/ja049968b]).Citations|Korzhnev04b}} * Korzhnev, D. M., Neudecker, P., Mittermaier, A., Orekhov, V. Y., and Kay, L. E. (2005). Multiple-site exchange in proteins studied with a suite of six NMR relaxation dispersion experiments: an application to the folding of a Fyn SH3 domain mutant. ''J. Am. Chem. Soc.'', '''127'''(44), 15602-15611. ([http{{#lst://dx.doi.org/10.1021/ja054550e 10.1021/ja054550e]).Citations|Korzhnev05a}}
== Links ==
== See also ==
[[Category:Models]]
[[Category:Dispersion models]]
[[Category:MMQ CPMG data]]
[[Category:Relaxation dispersion analysis]]
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